The long standing problem in the follow-up and treatment efficacy judgement is the assessment of the clinical state of the patient. Desk control methods are of little value due to the momentary aspect. The subjective scales used also turned out to be of little or no value. The need for long acting objective assessments is obvious. The development of the activity monitoring is very stimulating, which already proved its practical applicability. Further developments are necessary, as the device used is also not ideal.
The need for good asessments is illustrated int he second article of Ziegler and Ranoux. Only the subjective scales showed positive effects, whereas the semiquantitative scales failed to show any effect. in their open study they showed the advantages of a better compliances and a better swallowing in the patients using dispersible Madopar®. In the second part the effects of the dispersible formula is described in the afternoon akinesia. The findings, looking promising, need a controlled study with objective assessment scales.