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Mobile systems for monitoring Parkinson's disease
In this thesis, data from a mobile device test battery, collected during a three year clinical study, was used for the development and evaluation of methods. The data was gathered from a series of tests, consisting of selfassessments and motor tests (tapping and spiral drawing).
15 December 2013
Decision Support for Treatment of Patients with Advanced Parkinson's Disease
The overall aim of this thesis was to develop, deploy and evaluate new IT-based methods for supporting treatment and assessment of treatment of advanced Parkinson's disease.
23 October 2013
Preceding pain symptoms and Parkinson's disease: a nationwide population-based cohort study
Conclusions These findings support the hypothesis that pain is associated with PD in the pre-motor stage of the disease. Further research is needed to clarify the role of sensory system involvement in the pre-motor phase of PD.
17 May 2013
Initial cognitive dip after subthalamic deep brain stimulation in Parkinson disease
This study examined whether the rate of change in global cognitive function during the initial 6 months after STN DBS was different from the mean 6-month change that occurred between 6 and 36 months after surgery.
17 May 2013
Delusional misidentification syndrome and other unusual delusions in advanced Parkinson's disease
Conclusion: There are a few isolated reports of unusual neuropsychiatric disorders in patients with PD. Authors believe that these syndromes associated with advanced PD in elderly patients presenting with cognitive impairment and polypharmacy are probably often underestimated
16 May 2013
Mesencephalic area measured by transcranial sonography in the differential diagnosis of parkinsonism
Conclusions: Measurement of the mesencephalic area and the third ventricle width by TCS is a non-invasive, easily accessible technique that is useful in the differential diagnosis between PD and PSP, at least in the late stages of the disease.
16 May 2013
Urinary profile of catecholamines and metabolites in Parkinson patients with deep brain stimulation
Conclusion: After DBS-STN, the DA/l-DOPA ratio, an indirect measure of DA synthesis, increased. These results show that DBS-STN may improve the efficacy of oral levodopa.
16 May 2013
Human Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer
Past attempts to produce human NT-ESCs have failed secondary to early embryonic arrest of SCNT embryos. Here, authors identified premature exit from meiosis in human oocytes and suboptimal activation as key factors that are responsible for these outcomes.
15 May 2013
Co-occurring chronic conditions and healthcare expenditures associated with Parkinson's: A propensity score matched analysis
Among elderly, the average total expenditures were $15,404 for those with Parkinson's disease and $13,333 for those without Parkinson's disease. Results from regressions revealed that elderly with Parkinson's disease had 109% greater total expenditure compared to those without Parkinson's disease, when only demographic and socioeconomic variables were entered in the model.
15 May 2013
Motor outcomes during hospitalization in Parkinson's disease patients: A prospective study
Conclusions: This prospective study shows that a substantial part of hospitalized PD patients has a significant worse motor function at discharge mainly due to medication errors and infections. Quality of care could be improved by addressing preventable errors and allow patients to take control of their own Parkinson's disease medication.
15 May 2013
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