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The Addenbrooke's Cognitive Examination for the differential diagnosis and longitudinal assessment of patients with parkinsonianAuthors propose the ACE-R, particularly the verbal fluency subscore, as a valuable contributor to the differential diagnosis of parkinsonian syndromes in the correct clinical context. The ACE-R may reflect disease progression in PD and CBD. 20 May 2013
Exenatide and the treatment of patients with Parkinson's diseaseConclusion: These results demonstrate a potential cost-efficient approach through which preliminary clinical data of possible biological effects are obtainable, prior to undertaking the major investment required for double-blind trials of a potential disease-modifying drug in PD. 20 May 2013
Preceding pain symptoms and Parkinson's disease: a nationwide population-based cohort studyConclusions These findings support the hypothesis that pain is associated with PD in the pre-motor stage of the disease. Further research is needed to clarify the role of sensory system involvement in the pre-motor phase of PD. 17 May 2013
Initial cognitive dip after subthalamic deep brain stimulation in Parkinson diseaseThis study examined whether the rate of change in global cognitive function during the initial 6 months after STN DBS was different from the mean 6-month change that occurred between 6 and 36 months after surgery. 17 May 2013
Urinary profile of catecholamines and metabolites in Parkinson patients with deep brain stimulationConclusion: After DBS-STN, the DA/l-DOPA ratio, an indirect measure of DA synthesis, increased. These results show that DBS-STN may improve the efficacy of oral levodopa. 16 May 2013
Delusional misidentification syndrome and other unusual delusions in advanced Parkinson's diseaseConclusion: There are a few isolated reports of unusual neuropsychiatric disorders in patients with PD. Authors believe that these syndromes associated with advanced PD in elderly patients presenting with cognitive impairment and polypharmacy are probably often underestimated 16 May 2013
Mesencephalic area measured by transcranial sonography in the differential diagnosis of parkinsonismConclusions: Measurement of the mesencephalic area and the third ventricle width by TCS is a non-invasive, easily accessible technique that is useful in the differential diagnosis between PD and PSP, at least in the late stages of the disease. 16 May 2013
Co-occurring chronic conditions and healthcare expenditures associated with Parkinson's: A propensity score matched analysisAmong elderly, the average total expenditures were $15,404 for those with Parkinson's disease and $13,333 for those without Parkinson's disease. Results from regressions revealed that elderly with Parkinson's disease had 109% greater total expenditure compared to those without Parkinson's disease, when only demographic and socioeconomic variables were entered in the model. 15 May 2013
Motor outcomes during hospitalization in Parkinson's disease patients: A prospective studyConclusions: This prospective study shows that a substantial part of hospitalized PD patients has a significant worse motor function at discharge mainly due to medication errors and infections. Quality of care could be improved by addressing preventable errors and allow patients to take control of their own Parkinson's disease medication. 15 May 2013
A novel bedside task to tap inhibitory dysfunction and fronto-striatal atrophy in Parkinson's diseaseConclusions: The ELF is a brief bedside task that efficiently detects inhibitory dysfunction in non-demented PD. The utility of this novel behavioural measure is further substantiated by its anatomical specificity for fronto-striatal inhibitory control regions. 15 May 2013

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