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Parkinson disease: Interactive WalkMate system improves gait and stability in patients with Parkinson disease
Interactive rhythmic auditory stimulation can improve gait and stability in patients with Parkinson disease (PD), according to a new study published in PLoS ONE.
01 May 2012
A randomized, double-blind trial of transcranial electrostimulation in early Parkinson's disease.
The treatment was well tolerated without device-related adverse events. Despite the negative study, nonpharmacological approaches should continue to be pursued in Parkinson's disease, as they are generally well received by patients
15 July 2011
Quantitative magnetic resonance spectroscopic imaging in Parkinson's disease, PSP and MSA
Magnetic resonance spectroscopy (MRS) allows the measurement of a number of brain tissue metabolites in vivo, including N-acetylaspartate (NAA), a putative marker of neuronal integrity. Unlike single voxel MRS, magnetic resonance spectroscopic imaging (MRSI) enables quantification of these metabolites simultaneously from multiple anatomically localized voxels.
01 September 2010
Biomarkers: Parkinson disease with dementia and dementia with Lewy bodies
Dementia is a common feature in Parkinson disease (PD), the time of onset determining how patients are classified. Those patients where dementia develops prior to parkinsonism or during the first year of disease are designated as having dementia with Lewy bodies (DLB).
23 March 2010
Association of anosmia with autonomic failure in Parkinson disease
In Parkinson disease, anosmia is associated with baroreflex failure and cardiac and organ-selective extracardiac noradrenergic denervation, independently of parkinsonism or striatal dopaminergic denervation.
19 January 2010
T(1ρ) and T(2ρ) MRI in the evaluation of Parkinson's disease
This study provides additional validation of T(1rho) and T(2rho) as a means to separate PD from control subjects, and T(1rho) may be a useful marker of asymmetry in PD.
08 January 2010
In vivo amyloid imaging in autopsy-confirmed Parkinson's disease with dementia
To investigate the specificity of in vivo amyloid imaging with [(11)C]-Pittsburgh Compound B (PIB) in Parkinson disease dementia (PDD).
06 January 2010
Diagnosing premotor Parkinson's disease using a two-step approach combining olfactory testing and DAT SPECT imaging
The results of our studies provide the proof-of-principle that a two-step approach of olfactory testing and DAT SPECT imaging may serve to diagnose PD in its premotor phase.
01 December 2009
Molecular Imaging Studies in Parkinson Disease: Reducing Diagnostic Uncertainty
Since the introduction of in vivo molecular imaging techniques using Single-Photon Emission Computed Tomography and Positron Emission Tomography, the diagnosis of PD became more reliable by assessing dopaminergic and even nondopaminergic systems.
01 January 2009
Assessment of Parkinson's disease with imaging
In this article the value of structural and functional imaging in aiding the diagnosis and management of Parkinson's disease is reviewed.
01 September 2007
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