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Devices research papers
Time to get a move on: Overcoming bradykinetic movement in Parkinson's with artificial sensory guidance from biological motion
In this paper authors present novel evidence supporting the idea that the key to understanding paradoxical kinesia lies in both spatial and temporal information conveyed by the cues and the coupling between perception and action.
15 September 2013
Technical aids & housing adaptations among very old people with self-reported Parkinson's compared to matched controls
Results: Very old people with self-reported Parkinson's disease use significantly more aids for personal mobility than very old people in general. They have, furthermore, a significant increased unmet need concerning aids for personal care and protection. Housing adaptations did not differ between the two groups.
11 June 2013
Parkinson disease: Interactive WalkMate system improves gait and stability in patients with Parkinson disease
Interactive rhythmic auditory stimulation can improve gait and stability in patients with Parkinson disease (PD), according to a new study published in PLoS ONE.
01 May 2012
A randomized, double-blind trial of transcranial electrostimulation in early Parkinson's disease.
The treatment was well tolerated without device-related adverse events. Despite the negative study, nonpharmacological approaches should continue to be pursued in Parkinson's disease, as they are generally well received by patients
15 July 2011
Quantitative magnetic resonance spectroscopic imaging in Parkinson's disease, PSP and MSA
Magnetic resonance spectroscopy (MRS) allows the measurement of a number of brain tissue metabolites in vivo, including N-acetylaspartate (NAA), a putative marker of neuronal integrity. Unlike single voxel MRS, magnetic resonance spectroscopic imaging (MRSI) enables quantification of these metabolites simultaneously from multiple anatomically localized voxels.
01 September 2010
Biomarkers: Parkinson disease with dementia and dementia with Lewy bodies
Dementia is a common feature in Parkinson disease (PD), the time of onset determining how patients are classified. Those patients where dementia develops prior to parkinsonism or during the first year of disease are designated as having dementia with Lewy bodies (DLB).
23 March 2010
Association of anosmia with autonomic failure in Parkinson disease
In Parkinson disease, anosmia is associated with baroreflex failure and cardiac and organ-selective extracardiac noradrenergic denervation, independently of parkinsonism or striatal dopaminergic denervation.
19 January 2010
T(1ρ) and T(2ρ) MRI in the evaluation of Parkinson's disease
This study provides additional validation of T(1rho) and T(2rho) as a means to separate PD from control subjects, and T(1rho) may be a useful marker of asymmetry in PD.
08 January 2010
In vivo amyloid imaging in autopsy-confirmed Parkinson's disease with dementia
To investigate the specificity of in vivo amyloid imaging with [(11)C]-Pittsburgh Compound B (PIB) in Parkinson disease dementia (PDD).
06 January 2010
Diagnosing premotor Parkinson's disease using a two-step approach combining olfactory testing and DAT SPECT imaging
The results of our studies provide the proof-of-principle that a two-step approach of olfactory testing and DAT SPECT imaging may serve to diagnose PD in its premotor phase.
01 December 2009
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