[Skip to content]

European Parkinson's Disease Association
Search our Site
.

Research papers

Search

Measurement and diagnosis research papers

  • Man with stick Objective biomarkers of balance and gait for Parkinson's disease using body-worn sensorsThis review summarizes the types of objective measures available from body-worn sensors. The metrics are organized based on the neural control system for mobility affected by PD: postural stability in stance, postural responses, gait initiation, gait (temporal-spatial lower and upper body coordination and dynamic equilibrium), postural transitions, and freezing of gait. 15 September 2013
  • Brain scan Imaging: What can it tell us about parkinsonian gait?These findings illustrate the emergence of dopamine non-responsive gait problems to reflect the transition from a predominantly hypodopaminergic disorder to a multisystem neurodegenerative disorder involving non-dopaminergic locomotor network structures and pathologies. 15 September 2013
  • Pulse graph Quantitative wearable sensors for objective assessment of Parkinson's diseaseThis review discusses promising wearable technology, addresses which parameters should be prioritized in such assessment strategies, and reports about studies that have already investigated daily life issues in PD using this new technology. 12 September 2013
  • Chart Graph Rankin scale as a potential measure of global disability in early Parkinson's diseaseAuthors conducted an exploratory analysis of the utility of the modified Rankin Scale (mRS) as a global measure of disability in early Parkinson's diesase (PD) using the baseline data from a large cohort of PD patients enrolled in a longitudinal study of creatine. 01 September 2013
  • Brain skeleton activity Is there a need to redefine Parkinson's disease?A key challenge in PD research, therefore, is to better characterize markers for the 'preclinical' stages of the illness. Development of PD criteria by combining such markers allowing for an early diagnosis and intervention could pave the way for the design and implementation of future disease modification trials. 01 September 2013
  • Survey Handwriting as an objective tool for Parkinson's disease diagnosisIn this pilot study authors identified two simple short and routine writing tasks which differentiate PD patients from healthy controls. These writing tasks have future potential as cost-effective, fast and reliable biomarkers for PD. 01 September 2013
  • Brain activity Handwriting as an objective tool for Parkinson's disease diagnosisIn this pilot study we identified two simple short and routine writing tasks which differentiate PD patients from healthy controls. These writing tasks have future potential as cost-effective, fast and reliable biomarkers for PD. 01 September 2013
  • Neuron Biomarkers in Parkinson's disease (recent update)This brief review describes the merits and limitations of recently discovered biomarkers and proposes coenzyme Q10, mitochondrial ubiquinone-NADH oxidoreductase, melatonin, α-synculein index, Charnoly body, and metallothioneins as novel biomarkers to confirm PD diagnosis for early and effective treatment of PD. 01 September 2013
  • Brain scan A novel bedside task to tap inhibitory dysfunction and fronto-striatal atrophy in Parkinson's diseaseConclusions: The ELF is a brief bedside task that efficiently detects inhibitory dysfunction in non-demented PD. The utility of this novel behavioural measure is further substantiated by its anatomical specificity for fronto-striatal inhibitory control regions. 01 September 2013
  • Man with stick Clinical and posturographic correlates of falling in Parkinson's diseaseThe purpose of this study was to determine the efficacy of clinical tests, balance scales, and stable-platform posturography in detecting postural instability and discriminating between fallers and non-fallers in a home-dwelling PD cohort. 15 August 2013
Page: [10-] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [+21]