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Measurement and diagnosis research papers
Pisa syndrome in Parkinson's disease: Clinical, electromyographic, and radiological characterization
This study describes clinical, electromyographic (EMG), and radiological features of PS in a group of 20 PD patients. All patients with trunk deviation underwent EMG and radiological (RX and CT scan) investigation.
15 February 2012
Questionnaire for impulsive-compulsive disorders in Parkinson's DiseaseRating Scale
The QUIP-RS appears to be valid and reliable as a rating scale for impulse control disorders and related disorders in PD. Preliminary results suggest that it can be used to support a diagnosis of these disorders, as well as to monitor changes in symptom severity over time.
15 February 2012
Role of DaTSCAN and clinical diagnosis in Parkinson's disease
In the absence of neuropathologic validation, the overall accuracy of a clinical diagnosis of PD is very high and mathematically identical to the accuracy of DaTSCAN imaging, which calls into question the use of radiotracer neuroimaging as a diagnostic tool in clinical practice.
08 February 2012
Widespread cortical and subcortical brain atrophy in Parkinson's disease with excessive daytime sleepiness
PD patients with EDS, even without dementia and hallucination, showed significant gray matter atrophy compared to PD patients without EDS and controls.
01 February 2012
Drug and treatment costs in Parkinson's disease patients in Sweden
The study estimates high direct costs in patients with PD in Sweden, SEK 1.7 billion, 52% for inpatient care, 27% for outpatient care and 21% for drugs. without levodopa-induced dyskinesias.
01 February 2012
The Senior Fitness Test as a functional measure in Parkinson's disease: A pilot study
The SFT appears to be a useful tool to assess functional fitness in people with PD: it can be carried out in the clinical setting albeit with some minor modifications. However, its validity as an indicator of disease severity remains to be confirmed.
01 February 2012
Plasma-Based Circulating MicroRNA Biomarkers for Parkinson's Disease
Conclusions: This proof-of-concept study demonstrates the feasibility of using plasma-based circulating miRNAs as biomarkers for neurodegenerative disorders such as PD and shows the challenges of molecular biomarker research using samples from multiple clinical sites.
20 January 2012
Validation of the non-motor symptoms questionnaire (NMS-Quest)
Overall, this questionnaire can be a useful clinical tool for screening non-motor problems in an office setting.
01 January 2012
Assessing the utility of Freezing of Gait Questionnaires in Parkinson's Disease
This study demonstrate a potential role for sAPPα and sAPPβ in distinguishing between PS, a finding that needs to be confirmed in future studies of larger cohorts. There is a tendency towards low levels of Aβ(1-42) in DLB patients in this cohort.
01 January 2012
Mood disorders in Parkinson's disease
The development and validation of diagnostic criteria and rating scales for these disorders remain a priority particularly in relation to anxiety and apathy. Another gap in the management of these disorders is the limited empirical evidence for the treatment of these problems.
01 January 2012
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