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Measurement and diagnosis research papers

Quantitative EEG as a predictive biomarker for Parkinson disease dementiaThe QEEG measures of background rhythm frequency and relative power in the θ band are potential predictive biomarkers for dementia incidence in PD. 12 July 2011
Dementia associated with Parkinson's disease: Applying the Movement Disorder Society Task Force criteriaFindings suggest that the MDS-TF criteria are more sensitive than the DSM-IV for a diagnosis of PDD. Old age, absence of psychiatric symptoms, and severe motor impairment can hinder the diagnosis of PDD. 20 June 2011
Postprandial ghrelin response is reduced in patients with Parkinson's disease and idiopathic REM sleep behaviour disorderGhrelin, an orexigenic peptide, has multiple functions, which include promoting gastrointestinal motility and influencing higher brain functions. Experimental data suggest that ghrelin has neuroprotective potential in the MPTP mouse model of Parkinson's disease (PD). 02 June 2011
Summary of cerebrospinal fluid routine parameters in neurodegenerative diseasesIn neurodegenerative diseases, cerebrospinal fluid analysis (CSF) is predominantly performed to exclude inflammatory diseases and to perform a risk assessment in dementive disorders by measurement of tau proteins and amyloid beta peptides. However, large scale data on basic findings of CSF routine parameters are generally lacking. 01 June 2011
Lateral ventricle volume is poor predictor of post unilateral DBS motor change for Parkinson's diseaseVentricular volume was a poor predictor of acute motor change following DBS. Asymmetrical ventricles may not be a consistent imaging marker for PD motor dysfunction. 01 June 2011
Parkinson's disease risk score: moving to a premotor diagnosisIn this workshop report, the elements of a PD risk score are proposed, including the stepwise sequence of escalating diagnostic measures to diagnose the pre-motor stage in PD. 13 May 2011
Basic science in Parkinson's disease: its impact on clinical practiceThis review underlines the success of previous basic science for daily practice in PD and its impact for the understanding and development of an early diagnosis. Early, even pre-symptomatic diagnosis might be key to successfully establish disease-modifying treatments. 13 May 2011
Direct visualization of Parkinson's disease by in vivo human brain imaging using 7.0T magnetic resonance imagingThese results suggest that, by using 7.0T MRI, it appears possible to use these visible and distinctive changes in morphology as a diagnostic marker of PD. 15 March 2011
Phenotype of the 202 adenine deletion in the parkin gene: 40 years of follow-upThe 202A deletion of the parkin gene causes early-onset Parkinson's disease with marked levodopa/STN-DBSresistant axial features. Postural tremor and preserved cognition, even after 40 years of disease, were also evident. 15 March 2011
Arterial spin labelling reveals an abnormal cerebral perfusion pattern in Parkinson's diseaseA network approach, supported by arterial spin labelling-derived absolute perfusion values may provide a readily accessible neuroimaging method to characterize and track progression of both motor and cognitive status in Parkinson's disease. 09 March 2011

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