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Measurement and diagnosis research papers
Direct visualization of Parkinson's disease by in vivo human brain imaging using 7.0T magnetic resonance imaging
These results suggest that, by using 7.0T MRI, it appears possible to use these visible and distinctive changes in morphology as a diagnostic marker of PD.
15 March 2011
Phenotype of the 202 adenine deletion in the parkin gene: 40 years of follow-up
The 202A deletion of the parkin gene causes early-onset Parkinson's disease with marked levodopa/STN-DBSresistant axial features. Postural tremor and preserved cognition, even after 40 years of disease, were also evident.
15 March 2011
Arterial spin labelling reveals an abnormal cerebral perfusion pattern in Parkinson's disease
A network approach, supported by arterial spin labelling-derived absolute perfusion values may provide a readily accessible neuroimaging method to characterize and track progression of both motor and cognitive status in Parkinson's disease.
09 March 2011
T1rho (T(1ρ)) MR imaging in Alzheimer' disease and Parkinson's disease with and without dementia
In the current study, we aim to measure T1rho (T (1ρ)) in the hippocampus in the brain of control, Alzheimer's disease (AD), Parkinson's disease (PD), and PD patients with dementia (PDD), and to determine efficacy of T (1ρ) in differentiating these cohorts.
07 March 2011
Anxiety rating scales in Parkinson's disease: A validation study of the Hamilton anxiety rating scale, the Beck anxiety inventor
Given the adequate known groups validity of all three rating scales, each of these scales is likely to be useful in clinical practice or research for evaluation of symptom severity.
07 March 2011
Patient versus informant reporting of ICD symptoms in Parkinson's disease using the QUIP: Validity and variability
Overall, a negative QUIP from either the patient or informant rules out the possibility of an ICD, while a positive QUIP requires a follow-up diagnostic interview and ongoing monitoring to determine if symptoms currently are, or in the future become, clinically significant.
02 March 2011
Testing balance and fall risk in persons with Parkinson disease, an argument for ecologically valid testing
In order to most accurately identify fallers, clinicians should test persons with PD in ecologically relevant conditions and tasks. In this study, interpretation of the OFF medication performance and use of the FGA provided more accurate prediction of those who would fall.
01 March 2011
LINGO1 gene analysis in Parkinson's disease phenotypes
Study results indicate that LINGO1 variants could increase risk of PD, specifically those presenting the non-rigid-akinetic phenotypes, which suggests that LINGO1 may have a role in the etiology of tremor in PD at least in the Spanish population.
01 March 2011
Sonographic abnormalities in idiopathic restless legs syndrome (RLS) and RLS in Parkinson's disease
The study found that the RLS-PD group's sonological results and clinical findings were different from those of the iRLS group.
01 March 2011
A magnetization transfer study of mild and advanced Parkinson's disease
Magnetization transfer ratio (MTR) technique has identified brain changes in grey and white matter in Parkinson's disease (PD), even in the early phase.
01 March 2011
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