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Quality of life (QoL)
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Quality of life (QoL) research papers
Health-related quality of life in patients with parkinson's disease: Implications for falling
Results: All domains of the SF-36, except Role Emotional, were significantly lower among fallers. After controlling for potential confounding factors, the domain of Role Physical (p=0.027), Physical Composite Score (p=0.023) and the total SF-36 score (p=0.029) were significant predictors of occurrence of falls within one year of follow-up.
01 June 2015
A longitudinal study of non-motor symptom burden in Parkinson's disease after a transition to expert care
Conclusion: There was a significant reduction of total NMS burden over the study period. The severity of motor and activity of daily living impairments as well as subsequent visit were the best predictors of NMS change.
16 May 2015
The safety of istradefylline for the treatment of Parkinson's disease
This narrative review aims to discuss the safety and tolerability of istradefylline against the background of the currently available drug portfolio for the treatment of PD patients.
01 May 2015
Neuropsychiatric symptoms and caregiver's burden in Parkinson's disease
Conclusions: NPS in PD are highly associated with and are determinants of caregiver burden, and are more prevalent and burdensome in patients with dementia. Detailed assessment and specific interventions aimed at NPS could alleviate caregiver burden
09 April 2015
Mindfulness Training among Individuals with Parkinson's Disease: Neurobehavioral Effects
Results. Significant changes after the MBI were found including a 5.5 point decrease on the UPDRS motor score, an increase of 0.79 points on Parkinson's disease questionnaire (PDQ-39) pain item, and a 3.15 point increase in the Five Facet Mindfulness Questionnaire observe facet.
06 April 2015
Tango for treatment of motor and non-motor manifestations in Parkinson's disease: A Randomized control study
Conclusion: Argentine tango can improve balance, and functional mobility, and may have modest benefits upon cognition and fatigue in Parkinson's disease. These findings must be confirmed in longer-term trials explicitly powered for cognition and fatigue.
01 April 2015
Apathy in Parkinson's disease: A systematic review and meta-analysis
Authors found that apathy affects almost 40% of patients with PD. Several factors influence reported prevalence rates, contributing to the considerable heterogeneity in study results. Half of patients with apathy do not suffer from concomitant depression or cognitive impairment, confirming its status as a separate clinical syndrome in PD.
18 March 2015
Helicobacter Pylori infection is associated with worse severity of parkinson's disease
This is the largest cross-sectional study to demonstrate an association between HP positivity and worse PD motor severity.
01 March 2015
Preoperative brain metabolism and quality of life after subthalamic nucleus stimulation in Parkinson's disease
STN-DBS may have interfered with this already abnormal circuitry, leading to the occurrence of complex nonmotor symptoms reducing quality of life. Preoperative brain metabolism could be a useful biomarker for anticipating STN-DBS efficacy in terms of HRQoL in the context of advanced PD.
30 January 2015
The major impact of freezing of gait on quality of life in Parkinson's disease
While sleepwake disturbance and mood have a significant negative impact on HRQoL in PD, the emergence of FOG represents the most substantial predictor among patients in the earlier clinical stages of disease.
01 January 2015
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