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Quality of life (QoL) research papers

A Second Honeymoon for Parkinson's Disease?Medical therapy for Parkinson's disease is most effective in treating the motor symptoms of resting tremor, bradykinesia, and rigidity. Levodopa remains the most effective current treatment for motor symptoms; . . . 14 February 2012
Complaints about impairments in executive functions in Parkinson's disease: The association with neuropsychological assessmentPD patients were aware of problems with executive functions in daily life and reported considerably more problems than healthy controls. These problems were however not reflected by neuropsychological tests and may indicate a lack of ecological validity of neuropsychological assessment. 01 February 2012
Appreciation of humor is decreased among patients with Parkinson's diseaseConclusions: Patients with PD have a decreased sense of humor compared to healthy controls. Utilizing audio methods of presentation and humor in an obvious mode appears to be the preferred approach for eliciting responses to humor in a PD population. 01 February 2012
Loss of ability to work and ability to live independently in Parkinson's diseaseHigher UPDRS dyskinesia score, UPDRS instability score, UPDRS total score, Hoehn and Yahr stage, and presence of intellectual impairment at baseline were all associated with increased risk of future loss of ability to work and loss of ability to live independently (P 0.0033). Five years after initial visit, for patients 70 years of age with a disease duration 4 years at initial visit, 88% were still able to work and 90% to live independently. 01 February 2012
Relationships between motor aspects of gait impairments and activity limitations in people with PD: A systematic reviewThe objective of this review is to investigate the relationships between gait impairments and activity limitations in people with idiopathic PD. Six electronic databases (MEDLINE ISI, CINAHL, Web of Science ISI, EMBASE, PsycINFO and Scopus) were systematically searched using relevant terms to source for English-language studies published between 1900 and January 2011. 01 February 2012
Improving Community Healthcare for Patients with Parkinson's Disease: The Dutch ModelTo overcome the identified barriers, a tertiary referral centre was founded; evidence-based guidelines were developed and cost-effectively implemented within regional community networks of specifically trained allied health professionals (the ParkinsonNet concept). This increasingly uses ICT to bind these professional networks together and also to empower and engage patients in making decisions about their health. 01 February 2012
Are Verbal Fluency and Nonliteral Language Comprehension Deficits Related to Depressive Symptoms in Parkinson's Disease?As some language impairments in PD become apparent when depressive symptoms are associated with the disease, it would appear to be important to take the presence of depressive symptoms into account when evaluating language abilities in PD. 01 February 2012
Biopsychosocial and Spiritual Aspects of Parkinson Disease: An Integrative ReviewThe purpose of this study is to systematically examine the scientific literature and report the biopsychosocial and spiritual aspects of persons with Parkinson disease and their adaptation to the disease, to discuss methodological challenges associated with researching this phenomenon, and to propose future research 01 February 2012
Weekly exercise does not improve fatigue levels in Parkinson's diseaseSixty-five percent of the study group were fatigued (n = 24, mean 4.02, SD 1.48). Increased fatigue was associated with lower mobility and activity (P < .05). Individuals participated in a mean of 15 (SD 10) exercise sessions with no significant change in fatigue, mobility, well-being, or physical activity after exercise (P .05). 15 January 2012
Relationships between disability, quality of life and prevalence of nonmotor symptoms in Parkinson's diseaseDisability and quality of life assessment tools measure psychosocial facets that are similar specifically with regard to physical health component of health-related quality of life, are sensitive enough to capture differences related to disease's progression and increased prevalence of NMS. 01 January 2012

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