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Quality of life (QoL) research papers
Rasch analysis of the carers quality of life questionnaire for parkinsonism
Conclusion: The results suggest that the Carers Quality of Life Questionnaire for Parkinsonism is a useful scale to assess carers' quality of life and allows analyses requiring interval scaling of variables
22 November 2016
The non-motor side of the honeymoon period of Parkinson's & its relationship with quality of life: a 4-year longitudinal study
Conclusions: Non-motor symptoms significantly increase over time, with a different progression rate for each one. NMSs significantly affect quality of life in PD and we here demonstrated that this was especially the case when patients were in their (motor) honeymoon period. Future trials should target non-dopaminergic networks and consider NMSs in their outcomes.
01 November 2016
Aerobic Exercise Preserves Olfaction Function in Individuals with Parkinson's Disease
Results. Change in UPSIT scores between the exercise and nonexercise groups from baseline to EOT (p = 0.01) and from baseline to EOT+4 (p = 0.02) favored the aerobic exercise group. Individuals in the nonexercise group had worsening olfaction function over time, while the exercise group was spared from decline.
24 October 2016
Cognition and Parkinson's Disease: the Patient's Perspective
While changes in cognition are common in people with Parkinson's disease, there is limited understanding about how individuals perceive cognitive difficulties and how it impacts everyday activities. This report provides not only more understanding about this complex symptom, but also more information for patients, family and friends, caregivers, and clinicians.
20 October 2016
Anatomical and functional correlates of persistent pain in parkinson's disease
The study showed that persistent pain in PD is associated with supraspinal structural and functional changes. We also highlighted the contribution of frontal, prefrontal, and insular areas in nociceptive modulation and accumbenshippocampus disconnection
05 October 2016
Technology in Parkinson's disease: Challenges and opportunities
This article summarizes the work carried out by the task force toward identifying challenges and opportunities in the development of technologies with potential for improving the clinical management and the quality of life of individuals with PD.
01 September 2016
Predictors of functional dependency in Parkinson's disease
Authors analyzed data from the Parkinsonism Incidence in North-East Scotland (PINE) study, a prospective, community-based incident cohort of PD with ongoing follow-up. They described the development of dependency defined by a Schwab & England score of < 80% and a Barthel Index of <19. We identified the baseline predictors of dependency using multivariable Cox regression.
22 August 2016
Advanced therapies in Parkinson's disease: Long-term retrospective study
Conclusions: STN-DBS and LCIG showed comparable efficacy in ADL and OFF time, superior to OMT. STN-DBS yielded greater improvement in dyskinesia and lower long-term rate of complications than LCIG.
15 August 2016
Limb-kinetic apraxia affects activities of daily living in Parkinson's disease: a multi-center study
Conclusions: Constituting the novel key finding, limb-kinetic apraxia seems to be particularly relevant for ADL requiring dexterity skills in PD, even at early to moderate disease stages. Our results prompt research into the pathophysiological background and therapeutic options to treat limb-kinetic apraxia. The simple coin rotation test provides valuable information about ADL-related dexterity skills.
01 August 2016
Quality of life in Parkinson's disease improved by apomorphine pump: the OPTIPUMP cohort study
OPTIPUMP was a prospective, open-label, observational cohort study involving 30 investigational sites in France. CSAI was proposed as part of routine clinical care to patients aged 18 years, in absence of dementia, with a PD diagnosis and based on the presence of motor fluctuations not controlled by oral treatments.
01 June 2016
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