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Quality of life (QoL) research papers

Complaints about impairments in executive functions in Parkinson's disease: The association with neuropsychological assessmentPD patients were aware of problems with executive functions in daily life and reported considerably more problems than healthy controls. These problems were however not reflected by neuropsychological tests and may indicate a lack of ecological validity of neuropsychological assessment. 01 February 2012
Appreciation of humor is decreased among patients with Parkinson's diseaseConclusions: Patients with PD have a decreased sense of humor compared to healthy controls. Utilizing audio methods of presentation and humor in an obvious mode appears to be the preferred approach for eliciting responses to humor in a PD population. 01 February 2012
Nonmotor manifestations of Parkinson's diseaseIn addition, a number of nonmotor manifestations can precede the onset of motor symptoms in PD and can be used as screening tools allowing for early disease identification and for trials of possible disease-modifying interventions. This article reviews depression, sleep, and autonomic dysfunction in PD. 25 January 2012
Prevalence of pain in Parkinson's: A systematic review using the modified QUADAS toolSurprisingly, only 52.4% of PD patients with pain used analgesics, most often nonopioids. PD patients seem to be predisposed to develop pain and physicians should be aware of pain as a common feature of PD. 09 January 2012
Relationships between disability, quality of life and prevalence of nonmotor symptoms in Parkinson's diseaseDisability and quality of life assessment tools measure psychosocial facets that are similar specifically with regard to physical health component of health-related quality of life, are sensitive enough to capture differences related to disease's progression and increased prevalence of NMS. 01 January 2012
Lack of information and access to advanced treatment for Parkinson's disease patientsDoctors only provided a small proportion of patients with advanced therapy information, despite patients' interest. Hence, improvement is warranted regarding doctor appointments, information about various advanced treatment options, and their availability. 01 December 2011
Physical inactivity in Parkinson's diseaseThe study quantified daily physical activities in a large cohort of PD patients and another large cohort of matched controls. Moreover, it investigated the influence of disease-related factors on daily physical activities in PD patients. 01 December 2011
Impact of Anxiety on Quality of Life in Parkinson's DiseaseStepwise regression analyses revealed that anxiety explained 29% of the variance in the PDQ-39 sum score, and depression explained 10% of the variance beyond that accounted for by anxiety. The findings suggest that primary management of anxiety as well as depression may be important to optimizing the quality of life of PD patients. 01 December 2011
Changes in quality of life, burden and mood among spouses of Parkinson's disease patients receiving neurostimulationThe spouses' mean mood and quality of life scores changed little, while burden improved in younger spouses. There was no significant change in the spouses' overall status. However, at the individual level the effect of surgery was more frequently negative than positive. 28 November 2011
Depression and care-dependency in Parkinson's disease: Results from a nationwide study of 1449 outpatientsOlder age, longer duration and increased severity of PD contribute to care-dependency in patients with untreated depression. Treatment of depression is associated with lower rates of care-dependency. 28 November 2011

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